Science

Measure how your body changes

Make improved decisions based on stool biomarker data that is timely and accurate

Hands-free Stool Sample Collection

Convenience and dignity with no manual stool sampling

Personalized Insights

Inform healthy lifestyle and diet changes with actionable intelligence

Groundbreaking capabilities
Microbiome. Cancer. Crohn's and Colitis.

Morphological stool data was the first step of Coprata’s advanced stool analysis. The Sampling Toilet introduces the groundbreaking capability of automated hands-free collection of stool specimen, where stool is produced, eliminating the need of any physical, visual, or olfactory interaction.

The current gold standard is manual self-collection, which is considered unpleasant by most people and results in reluctance to repeated measurements. The Coprata solution offers unprecedented access to a specimen, facilitating frequent and long-term measurement of fecal biomarkers, instead of single snapshot test.
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Fecal biomarkers (gut microbiome, inflammatory proteins, and others) hold promise for the prediction of disease risk and response to therapy in illnesses such as chronic digestive diseases, cancers, and infections.
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The Coprata Toilet will enable new types of clinical research and the development of novel approaches to proactive health. Established stool biomarkers include occult (hidden) blood detected by the Fecal Immunochemical Test (FIT), a non-invasive screening for colon cancer, and the inflammatory protein calprotectin, whose rising values predict flare-ups in Crohn's disease and ulcerative colitis. Many more biomarkers are to be discovered.

The Coprata Toilet paves the way for new medical research and discovery and represents a convenient tool to monitor specific early warning of disease and to track the effectiveness of therapies.

Our Evidence

Scientific publications and presentations

Jin Zhou, Yuying Luo, Julia W. Darcy, Kyle J. Lafata, Jose R. Ruiz, and Sonia Grego. 2025 "Long‐term, automated stool monitoring using a novel smart toilet: A feasibility study." Neurogastroenterology & Motility 37: e14954.

Sonia Grego, Walker G. Resney, Brian Stoner, Sameer K. Berry, William D. Chey, and Borko Nojkov. 2024 "Sa2011 Novel Automated Smart Toilet Allows Objective Longitudinal Assessment Of Bowel Movements-Preliminary, Home-Based, Experience ", Gastroenterology, 166: S-601-S-02.

Sonia Grego, Jin Zhou, Jose R. Ruiz, Kyle Lafata, Brian Hawkins, and Yuying Luo. 2023. "S663 Long-Term, Non-Invasive, Objective Stool Monitoring Using a Novel Smart Toilet: A Feasibility Study", Official journal of the American College of Gastroenterology | ACG, 118: S484-S85.

Claire Welling, Brian T Hawkins, Amy Barto, Hans Herfarth, and Sonia Grego. 2023. "Smart Sampling Toilet-A Potential New Automated System For Collecting Fecal Calprotectin Samples", Gastroenterology, 164: S-54-S-55.

Sonia Grego, Claire M. Welling, Graham H. Miller, Peter F. Coggan, Katelyn L. Sellgren, Brian T. Hawkins, Geoffrey S. Ginsburg, Jose R. Ruiz, Deborah A. Fisher, and Brian R. Stoner. "A hands-free stool sampling system for monitoring intestinal health and disease." Scientific Reports 12, no. 1 (2022).

Claire Welling, David R. Singleton, Steven B. Haase, Christian H. Browning, Brian R. Stoner, Claudia K. Gunsch, and Sonia Grego. "Predictive values of time-dense SARS-CoV-2 wastewater analysis in university campus buildings." Science of The Total Environment (2022): 155401.

Sonia Grego, Jin Zhou, Krishnendu Chakrabarty, Brian R. Stoner, Jose R. Ruiz, Deborah A. Fisher. "Automated Stool Image Analysis for Artificial Intelligence in a Smart Toilet." Gastroenterology 160 (May 2021).

Jin Zhou, Nick DeCapite, Jackson McNabb, Jose R. Ruiz, Deborah A. Fisher, Sonia Grego, Krishnendu Chakrabarty. "Stool Image Analysis for Precision Health Monitoring by Smart Toilet." Proceedings of Machine Learning Research 149 (2021).

Learn more about the research https://smarttoilet.pratt.duke.edu/